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J. Bacteriol. doi:10.1128/JB.01088-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Role of DNA Polymerase IV in the E. coli SOS mutator activity

Institute of Biochemistry and Biophysics, Polish Academy of Sciences, 02 106 Warsaw, Poland , and Laboratory of Molecular Genetics, National Institute of Environmental Health Sciences, Research Triangle Park, NC 27709, USA

	Abstract

Constitutive expression of the SOS regulon in E. coli recA730 strains leads to a mutator phenotype (SOS mutator) that is dependent on DNA Polymerase V (UmuDC gene product). Here we show that a significant fraction of this effect also requires DNA Polymerase IV (dinB gene product).