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JB Accepts, published online ahead of print on 17 November 2006
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J. Bacteriol. doi:10.1128/JB.01125-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Derepression of Excision of Integrative and Potentially Conjugative Elements from Streptococcus thermophilus by DNA damage response: implication of a cI-related repressor

Xavier Bellanger, Catherine Morel, Bernard Decaris, and Gérard Guédon*

Laboratoire de Génétique et Microbiologie UMR1128, INRA, IFR110, Université Henri Poincaré Nancy 1, F-54506 Vandoeuvre-lès-Nancy, France

* To whom correspondence should be addressed. Email: guedon{at}nancy.inra.fr.


   Abstract

A DNA damaging agent, the mitomycin C, derepresses the site-specific excision of two integrative and potentially conjugative elements from Streptococcus thermophilus, ICESt1 and ICESt3. This regulation pathway involves a repressor related to phage lambda cI repressor. It could also involve a putative regulator related to another type of phage repressors, the "cI-like" repressors.







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