J. Bacteriol. doi:10.1128/JB.01125-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.
Derepression of Excision of Integrative and Potentially Conjugative Elements from Streptococcus thermophilus by DNA damage response: implication of a cI-related repressor
Xavier Bellanger,
Catherine Morel,
Bernard Decaris,
and
Gérard Guédon*
Laboratoire de Génétique et Microbiologie UMR1128, INRA, IFR110, Université Henri Poincaré Nancy 1, F-54506 Vand
uvre-lès-Nancy, France
* To whom correspondence should be addressed. Email:
guedon{at}nancy.inra.fr.
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Abstract |
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A DNA damaging agent, the mitomycin C, derepresses the site-specific excision of two integrative and potentially conjugative elements from Streptococcus thermophilus, ICESt1 and ICESt3. This regulation pathway involves a repressor related to phage lambda cI repressor. It could also involve a putative regulator related to another type of phage repressors, the "cI-like" repressors.