"Candidatus Cloacamonas acidaminovorans": genome sequence reconstruction provides a first glimpse of a new bacterial division

CEA/Genoscope, CNRS-UMR8030, Université d'Evry Val d'Essonne, 91057 Evry, France, Suez-Environnement CIRSEE, 78230 Le Pecq, France, Institut Pasteur, 75015 Paris, France

^* To whom correspondence should be addressed. Email: denis{at}genoscope.cns.fr.

	Abstract

Many microorganisms live in anaerobic environments. Most of these microorganisms have not yet been cultivated. Here we present, from a metagenomic analysis of an anaerobic digester of a municipal wastewater treatment plant, the reconstruction of the complete genome of a bacterium belonging to the WWE1 candidate division. In silico proteome analysis indicated that this bacterium might derive most of its carbon and energy from the fermentation of amino acids and hence was then provisionally classified as "Candidatus Cloacamonas acidaminovorans". C. acidaminovorans is probably a syntrophic bacterium which is present in many anaerobic digesters. This report highlights how environmental sequence data might provide genomic and functional information about a new bacterial clade, whose members are involved in anaerobic digestion.