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J. Bacteriol. doi:10.1128/JB.01456-06
Copyright (c) 2006, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

The Linker Regions of the RhaS and RhaR Proteins

Ana Kolin, Visnja Jevtic, Liskin Swint-Kruse, and Susan M. Egan*

Department of Molecular Biosciences, University of Kansas, Lawrence, KS 66045, USA; Department of Biochemistry and Molecular Biology, MS 3030

* To whom correspondence should be addressed. Email: sme{at}ku.edu.


   Abstract

Substitutions within the inter-domain linkers of the AraC/XylS family proteins RhaS and RhaR were tested to determine whether side chain identity or linker structure were required for function. Neither was found crucial, suggesting that the linkers don't play a direct role in activation, but rather simply connect the two domains.







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