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JB Accepts, published online ahead of print on 19 January 2007
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J. Bacteriol. doi:10.1128/JB.01619-06
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

Distantly Related SIC (DRS) is far less Divergent than SIC of Group A Streptococcus

Vivek Sagar, Rajesh Kumar, Nirmal K. Ganguly, Thangam Menon, and Anuradha Chakraborti*

Departments of Experimental Medicine and Biotechnology, Community Medicine PGIMER, Chandigarh, ICMR, New Delhi and Department of Microbiology, University of Madras, Chennai, India

* To whom correspondence should be addressed. Email: superoxide{at}sify.com.


  Abstract

On screening Group A Streptococcus (100) isolates, drs, a variant of sic, was identified in emm12 and emm55 isolates tested. Molecular characterization showed that drs gene sequence is highly conserved unlike SIC. However, the variation observed in gene size is due to the presence of extra internal repeat sequences.




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