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J. Bacteriol. doi:10.1128/JB.01854-06
Copyright (c) 2007, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

YhdJ, a non-essential CcrM-like DNA methyltransferase of Escherichia coli and Salmonella enterica

The Hull York Medical School and the Department of Biology, University of York, P. O. Box 373, York Y010 5YW, England; Departamento de Genética, Facultad de Biología, Universidad de Sevilla, Apartado 1095, Seville 41080, Spain; Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, 364 Plantation Street, Worcester, Massachusetts 01605 USA

^* To whom correspondence should be addressed. Email: mvdw1{at}york.ac.uk.

	Abstract

The Caulobacter crescentus DNA adenine methyltransferase CcrM and its homologs in alpha-Proteobacteria are essential for viability. CcrM is 34% identical to the yhdJ gene products of Escherichia coli and Salmonella enterica. This study provides evidence that the E. coli yhdJ gene encodes a DNA adenine methyltransferase. In contrast to an earlier report, however, we show that yhdJ is not an essential gene in either E. coli or in S. enterica.