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J. Bacteriol. doi:10.1128/JB.01889-07
Copyright (c) 2008, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved.

"The Gene Encoding Ribonuclease III in Streptomyces coelicolor is Transcribed During Exponential Phase and is Required for Antibiotic Production and for Proper Sporulation"

Department of Molecular Microbiology, John Innes Centre, Norwich Research Park, Colney, Norwich, NR4 7UH, United Kingdom

^* To whom correspondence should be addressed. Email: jason_sello{at}brown.edu.

	Abstract

Phenotypic analysis of a constructed ribonuclease III null mutant of Streptomyces coelicolor revealed that ribonuclease III is required for both antibiotic production and proper formation of sporulation septa. Transcriptional analysis of the gene encoding ribonuclease III indicates that it is transcribed exclusively during exponential phase as part of a tricistronic message.

This article has been cited by other articles:

• Xu, W., Huang, J., Cohen, S. N. (2008). Autoregulation of AbsB (RNase III) Expression in Streptomyces coelicolor by Endoribonucleolytic Cleavage of absB Operon Transcripts. J. Bacteriol. 190: 5526-5530 [Abstract] [Full Text]