Cover photograph (Copyright © 2001, American Society for Microbiology. All rights reserved.): Methanol-grown cells of the methylotrophic yeast Candida boidinii expressing green fluorescent protein-peroxisomal catalase (Cta1)-fusion protein, showing a bimodal distribution of Cta1 between cytosol and peroxisomes. The green fluorescence and Nomarski images are superimposed and were adjusted with Adobe Photoshop. This bimodal distribution of a peroxisomal marker enzyme was unexpected and was not observed in oleate- or D-alanine-grown cells. (See related article on page 6372.)