Helicobacter pylori Flagellar Hook-Filament Transition Is Controlled by a FliK Functional Homolog Encoded by the Gene HP0906

Volume 187, no. 16, p. 5742-5750, 2005. Attempts to extend the observation of complementation of a Salmonella fliK mutant by HP0906 to orthologous genes led to the discovery that the apparent restoration of motility by expression of HP0906 in the Salmonella fliK mutant strain SJW108 was actually due to reversion of the fliK mutation. This reversion occurred in the transformant with the pQE60-HP0906 construct. Expression of HP0906 does not complement Salmonella fliK, and the apparent motility in Fig. 7C (labeled SJW108/pQE60-HP0906) is incorrect. The bioinformatic, ultrastructural, motility, and regulatory data identifying HP0906 as fliK are unaffected, and the main conclusion remains unchanged.

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