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GENETICS AND MOLECULAR BIOLOGY

Mutations in Conserved Helix 69 of 23S rRNA of Thermus thermophilus That Affect Capreomycin Resistance but Not Posttranscriptional Modifications

Tanakarn Monshupanee, Steven T. Gregory, Stephen Douthwaite, Wipa Chungjatupornchai, Albert E. Dahlberg
Tanakarn Monshupanee
1Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912
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Steven T. Gregory
1Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912
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Stephen Douthwaite
2Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark
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Wipa Chungjatupornchai
3Institute of Molecular Biology and Genetics, Mahidol University, Salaya Campus, Nakornpathom 73170, Thailand
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Albert E. Dahlberg
1Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912
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  • For correspondence: AE_Dahlberg@Brown.edu
DOI: 10.1128/JB.00984-08
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Article Information

DOI 
https://doi.org/10.1128/JB.00984-08
PubMed 
18805973

Published By 
American Society for Microbiology Journals
History 
  • Received July 16, 2008
  • Accepted September 11, 2008
  • Published online November 12, 2008.

Copyright & Usage 
Copyright © 2008 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (September 19, 2008).
  • You are viewing the most recent version of this article.

Author Information

  1. Tanakarn Monshupanee1,
  2. Steven T. Gregory1,
  3. Stephen Douthwaite2,
  4. Wipa Chungjatupornchai3 and
  5. Albert E. Dahlberg1*
  1. 1Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, Rhode Island 02912
  2. 2Department of Biochemistry and Molecular Biology, University of Southern Denmark, Odense M, Denmark
  3. 3Institute of Molecular Biology and Genetics, Mahidol University, Salaya Campus, Nakornpathom 73170, Thailand
  • ↵* Corresponding author. Mailing address: Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912. Phone: (401) 863-2223. Fax: (401) 863-1201. E-mail: AE_Dahlberg{at}Brown.edu
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Mutations in Conserved Helix 69 of 23S rRNA of Thermus thermophilus That Affect Capreomycin Resistance but Not Posttranscriptional Modifications
Tanakarn Monshupanee, Steven T. Gregory, Stephen Douthwaite, Wipa Chungjatupornchai, Albert E. Dahlberg
Journal of Bacteriology Nov 2008, 190 (23) 7754-7761; DOI: 10.1128/JB.00984-08

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Mutations in Conserved Helix 69 of 23S rRNA of Thermus thermophilus That Affect Capreomycin Resistance but Not Posttranscriptional Modifications
Tanakarn Monshupanee, Steven T. Gregory, Stephen Douthwaite, Wipa Chungjatupornchai, Albert E. Dahlberg
Journal of Bacteriology Nov 2008, 190 (23) 7754-7761; DOI: 10.1128/JB.00984-08
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KEYWORDS

Anti-Bacterial Agents
Capreomycin
Drug Resistance, Bacterial
RNA Processing, Post-Transcriptional
RNA, Ribosomal, 23S
Thermus thermophilus

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