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MICROBIAL COMMUNITIES AND INTERACTIONS

Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal

Nicolas Barraud, David Schleheck, Janosch Klebensberger, Jeremy S. Webb, Daniel J. Hassett, Scott A. Rice, Staffan Kjelleberg
Nicolas Barraud
1School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, University of New South Wales, Sydney, New South Wales 2052, Australia
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David Schleheck
1School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, University of New South Wales, Sydney, New South Wales 2052, Australia
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Janosch Klebensberger
1School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, University of New South Wales, Sydney, New South Wales 2052, Australia
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Jeremy S. Webb
1School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, University of New South Wales, Sydney, New South Wales 2052, Australia
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Daniel J. Hassett
2Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267
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Scott A. Rice
1School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, University of New South Wales, Sydney, New South Wales 2052, Australia
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Staffan Kjelleberg
1School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, University of New South Wales, Sydney, New South Wales 2052, Australia
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  • For correspondence: s.kjelleberg@unsw.edu.au
DOI: 10.1128/JB.00975-09
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Article Information

DOI 
https://doi.org/10.1128/JB.00975-09
PubMed 
19801410

Published By 
American Society for Microbiology Journals
History 
  • Received July 24, 2009
  • Accepted September 22, 2009
  • Published online November 9, 2009.

Copyright & Usage 
Copyright © 2009 American Society for Microbiology

Article Versions

  • Accepted Manuscript version (October 02, 2009).
  • You are viewing the most recent version of this article.

Author Information

  1. Nicolas Barraud1,
  2. David Schleheck1‡,
  3. Janosch Klebensberger1,
  4. Jeremy S. Webb1§,
  5. Daniel J. Hassett2,
  6. Scott A. Rice1 and
  7. Staffan Kjelleberg1*
  1. 1School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, University of New South Wales, Sydney, New South Wales 2052, Australia
  2. 2Department of Molecular Genetics, Biochemistry and Microbiology, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267
  • ↵* Corresponding author. Mailing address: School of Biotechnology and Biomolecular Sciences and Centre for Marine Bio-Innovation, Biological Sciences Building, University of New South Wales, Sydney, NSW 2052, Australia. Phone: 61 (2) 9385 2102. Fax: 61 (2) 9385 1779. E-mail: s.kjelleberg{at}unsw.edu.au
  • ↵‡ Present address: Department of Biology, University of Konstanz, D-78457 Konstanz, Germany.; § Present address: School of Biological Sciences, University of Southampton, Southampton SO16 7PX, United Kingdom.

  • † Supplemental material for this article may be found at http://jb.asm.org/ .

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Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal
Nicolas Barraud, David Schleheck, Janosch Klebensberger, Jeremy S. Webb, Daniel J. Hassett, Scott A. Rice, Staffan Kjelleberg
Journal of Bacteriology Nov 2009, 191 (23) 7333-7342; DOI: 10.1128/JB.00975-09

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Nitric Oxide Signaling in Pseudomonas aeruginosa Biofilms Mediates Phosphodiesterase Activity, Decreased Cyclic Di-GMP Levels, and Enhanced Dispersal
Nicolas Barraud, David Schleheck, Janosch Klebensberger, Jeremy S. Webb, Daniel J. Hassett, Scott A. Rice, Staffan Kjelleberg
Journal of Bacteriology Nov 2009, 191 (23) 7333-7342; DOI: 10.1128/JB.00975-09
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KEYWORDS

biofilms
Cyclic GMP
Gene Expression Regulation, Bacterial
nitric oxide
Phosphoric Diester Hydrolases
Pseudomonas aeruginosa
signal transduction

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