Table 1.

Identified motifs for 4′-phosphopantetheine cofactor attachment

Segment in acmclusteraSequence of core 6ACMS typeb
dom1D F F E L G G H S LII
dom 2D F F A L G G D S III
dom3D F F E L G G H S LIII
dom4D F F E L G G H S LIII
dom5D F F D L G G H S LIII
  • a Segments with respective motif positions are indicated in Fig. 1.

  • b Derived from sequencing acmB and the indicated fragments (Fig. 1) of the putative acmC gene region.