Table 4.

Effects of vie gene deletions on in vitro growth and colonization of infant mice

StrainGenotypeRatio of mutant to wild typea
In vitro competitionbIn vivo competitionc
  • a Ratio of test strain to virulent strain corrected for deviations in inoculum ratio from a value of 1:1.

  • b Cultures were grown in LB broth at 37°C for 24 h.

  • c Bacteria were recovered from the small intestines of infant CD-1 mice after 24 h. Each ratio represents the mean for eight animals.