Table 2.

Recovery of L. monocytogenes 10403S and the isogenic sigB mutant from tissues of infected mice after intragastric or intraperitoneal infection

Type of inoculation and tissueLog10 no. of bacteria/g of tissue (± SD) at the following day postinfectiona:
24
10403SsigBmutant10403SsigB mutant
Intragastric
 Liver3.7 (1.2)3.4 (1.3)3.7 (0.5)c 2.9 (0.4)c
 Spleen4.0 (1.0)4.1 (1.5)4.9 (0.4)4.5 (0.2)
Intraperitoneal
 Liver4.3 (0.5)b 3.6 (0.3)b 3.9 (1.5)4.3 (0.9)
 Spleen5.1 (0.4)4.8 (0.4)5.0 (1.5)5.1 (0.5)
  • a Values are the averages of five inoculated animals, except for the intragastric-inoculation day-2 data, which represent the averages of four animals (one animal was excluded from each group because fewer bacteria than the detection limit [10 CFU/g for liver and <102 CFU/g for spleen] were recovered).

  • b Bacterial numbers differ significantly atP = 0.029.

  • c Bacterial numbers differ significantly atP = 0.027.