Table 2.

Genotypic and phenotypic characterization ofN. meningitidis clinical isolates and isogenichpuB::erm andhmbR::kan derivatives

SerotypeClinical isolateshpuB::ermderivativeshmbR::kanderivatives
StrainhmbRahpuBaPHbStrainNo. of GcPHStrainPH
C2857++LW32728SC3303LW
2858++LW327313SC3304LW
2859++LW327412LW3305SC
2860++LW327510SC3306LW
2861++LWNTd*NANTNA
2862++LW327613SC3307LW
2863++LW327713SC3308LW
A2848++LW32659LWNTNA
2849++LWNT9NA3299SC
2850+LW3266*0NALW
2851++LW32679LW3300SC
2852+LW3268*0NALW
2853+LW3269*0NALW
2854+LWNT*NANALW
2855++LW32708SC3301SC
2856++LW32719LW3302SC
Y2843++LWNT10NANTNA
2844+03262*0NA0
2845+LW3263*0NALW
2846+LW3264*0NALW
2847++LWNT10NANTNA
B1074+LWNAe9LW32970
2781++SC32618SC3298SC
  • a Presence (+) or absence (−) of homologous sequence determined by Southern blot hybridization.

  • b The Hb utilization phenotype (PH) of the strain is as follows: LW, confluent lawn; SC, single colony; NA, not applicable; 0, no growth.

  • c Number of consecutive G residues in the poly(G) tract of hmbR. An asterisk indicates that no sequence was obtained.

  • d NT, no transformants obtained.

  • e NA, not available.