Table 5.

Point mutations

AlleleMutationStrainPhenotype
Amino acidaCodon
eutT77Q61AmCAG→TAGTT11494eut(N)
eutT62bQ62AmCAG→TAGTT11479eut(N)
eutT86P76L,Q77AmCCACAG→CTATATT11503eut(N)
eutT67Q77AmCAG→TAGTT11484eut(N)+
eutT10W125OpTGG→TGATT11518eut(N)+
eutT75Q127OcCAA→TAATT11492eut(N)+
eutT78Q134OpTGG→TGATT11406eut(N)+
eutT74Q177AmCAG→TAGTT11491eut(N)+
eutD64Q18AmCAG→TAGTT11481eut(N)+
eutD53Q35OcCAA→TAATT11470eut(N)
eutD10Q156AmCAG→TAGTT11515eut(N)+
eutD12R173OpCGA→TGATT11538eut(N)+
  • a Original amino acid (left) and substitution (right) flank the position of the affected codon in the gene. Nonsense codons are abbreviated as follows: Am, amber (TAG); Op, opal (TGA); Oc, ocher (TAA).

  • b Unlisted mutations eutT88(TT11505) and eutT90 (TT11507) are recurrences of the same mutation as listed mutation eutT62, i.e., Q184Am.