Table 1.

B. burgdorferi strains used in this study

StrainRelevant integrated DNADrug resistance phenotypeaKanamycin MIC (μg/ml)Source or reference
B31-ANone/wild typeCous Kans≤25This study
KS5kan gyrBrCour KansNDb30
AB1kan gyrBrCour Kans5030
KA1PflaB-kan gyrBrCour Kanr>1,600This study
KG1PflgB-kan gyrBrCour Kanr>1,600This study
AB5PflaB-kan ΔoppAVCous KanrNDThis study
  • a Kans, inability to form colonies in the presence of 40 μg of kanamycin per ml; Kanr, ability to form colonies in the presence of 200 μg of kanamycin per ml; Cous, inability to form colonies in the presence of 0.5 μg of coumermycin per ml; Cour, ability to form colonies in the presence of 0.5 μg of coumermycin per ml.

  • b ND, not determined.