Table 1.

B. burgdorferi strains used in this study

StrainRelevant integrated DNADrug resistance phenotypeaKanamycin MIC (μg/ml)Source or reference
B31-ANone/wild typeCous Kans ≤25This study
KS5 kan gyrBr Cour Kans NDb 30
AB1 kan gyrBr Cour Kans 50 30
KA1PflaB -kan gyrBr Cour Kanr >1,600This study
KG1PflgB -kan gyrBr Cour Kanr >1,600This study
AB5PflaB -kan ΔoppAVCous Kanr NDThis study
  • a Kans, inability to form colonies in the presence of 40 μg of kanamycin per ml; Kanr, ability to form colonies in the presence of 200 μg of kanamycin per ml; Cous, inability to form colonies in the presence of 0.5 μg of coumermycin per ml; Cour, ability to form colonies in the presence of 0.5 μg of coumermycin per ml.

  • b ND, not determined.