Table 1.

Distribution of mevalonate and GAP-pyruvate pathways for IPP biosynthesis

OrganismPresence of:Reference(s)
Mevaolonate pathwayGAP-pyruvate pathway
Gram-negative bacteria
Enterobacteriaceae, Haemophilus influenzae + 21,35, 37
B. burgdorferi, M. fulvus,C. ethylica + 21, 35
Gram-positive bacteria
Mycobacteria, B. subtilis + 35, 52
Streptomycesspp.a ++ 41
 Low-G+C gram-positive cocci+This study
Archaea+ 5, 6
Fungi+ 28
Higher plants
 Cytoplasmic+ 17
 Plastid+ 29
Algae+b +c 14,40, 43
Animals+ 17
  • a Some species of Streptomycespossess both pathways simultaneously.

  • b Including species such as S. obliquus, Chlorella fusca, and Chlamydomonas reinhardtii.

  • c Including species such as E. gracilis.