Table 5.

Expression of genes or DNA regions related to antibiotic production or polyketide biosynthesis in B. subtilis JH642 when grown under anaerobic conditionsa

GeneDescriptionInduction or repression (fold)
Nitrate respirationNitrite respirationFermentation
−Pyruvate+Pyruvate
sbo Subtilosin A14.433.566.142.3
albA Similar to protein for PQQ synthesis21.442.891.338.6
albB 8.018.231.016.1
albC Similar to ABC-type transporter8.915.037.018.8
albD 18.938.055.930.5
albE 29.740.154.038.6
albF Similar to processing peptidase beta subunit20.649.777.941.7
albG 4.714.226.98.0
sunA Sublancin 168 lantibiotic precursor8.811.56.17.7
pksB Polyketide biosynthesis1.82.43.72.4
pksC 2.76.012.16.1
pksD 3.710.121.811.2
pksE 2.26.19.03.9
pksF 1.96.77.46.1
pksG 2.27.74.69.1
pksH 1.65.82.86.0
pksI 1.95.62.97.3
  • a Growth conditions and data presentation are as described in Tables 1 and 2. −Pyruvate, without pyruvate; +Pyruvate, with pyruvate.