TABLE 2.

Distribution of essential and nonessential genes and average ERIs in selected functional categoriesa

Functional categoryDescriptionTotal no. of ORFsNo. ENo. NNo. ?No. ND% EMean ERI
AAMAmino acid metabolism1382110818150.5
CHMCarbohydrate metabolism21921178317100.4
NCMNucleotide and cofactor metabolism1815311927290.5
LPCLipid, lipopolysaccharide, lipoprotein, peptidoglycan, and cell wall biosynthesis1263473514270.5
NAMNucleic acid metabolism1564396512280.6
PMSProtein metabolism and secretion16780571812480.7
MSMMiscellaneous metabolism94147226150.4
BENBioenergetics100157546150.3
SMCSignaling, motility, and chemotaxis1531212531380.3
RCDExpression regulation and cell cycle and division177301181316170.2
MTRMembrane transport276222443780.3
PHTPhage- and transposase-related processes621235213190.3
CATAll categorized1,8493571,30061131190.4
UNCUncategorized2,4422631,826157196110.2
TotalCategorized and uncategorized4,2916203,126218327140.3
  • a Abbreviations are as follows: E, essential; N, nonessential; ND, not determined; ?, ambiguous.