TABLE 1.

High-salinity-induced genes

GeneaFunctionbSignal strength ratioc for cells growing in MM with:
1.2 M NaCl, 5 μM Fe1.2 M NaCl, 250 μM Fe
bofAInhibition of the pro-sigma-K processing machinery3.21.2
yabEUnknown; similar to cell wall-binding protein5.45.7
ksgADimethyladenosine transferase4.44.8
opuAAGlycine betaine ABC transporter (ATP-binding protein)4.34.8
opuABGlycine betaine ABC transporter (permease)3.23.7
opuACGlycine betaine ABC transporter (glycine betaine-binding protein)4.73.9
ydcEUnknown; similar to unknown proteins3.13.0
ydcKUnknown; similar to unknown proteins3.23.4
ydcOUnknown3.15.2
yddJUnknown13.89.8
yddTUnknown3.31.9
groESClass I heat shock protein (chaperonin)3.53.7
yflJUnknown3.43.1
yfjQUnknown; similar to divalent cation transport protein3.22.3
yfjCUnknown4.15.0
yfjBUnknown6.710.2
yfjAUnknown5.47.2
yhaAUnknown; similar to aminoacylase3.24.4
yhjMUnknown; similar to transcriptional regulator (LacI family)7.06.5
yitMUnknown; similar to unknown proteins from B. subtilis4.02.6
yjcEUnknown3.32.4
yjhAUnknown4.24.5
yjiAUnknown4.13.1
ykaAUnknown4.92.5
yklAUnknown; similar to unknown proteins3.44.6
ykrIUnknown3.74.8
ykwDUnknown; similar to unknown proteins from B. subtilis3.43.4
ykuHUnknown6.85.7
ykzFUnknown3.12.7
ykuLUnknown; similar to unknown proteins4.75.1
ylbAUnknown; similar to unknown proteins4.13.9
ylbBUnknown; similar to IMP dehydrogenase4.43.4
ylbCUnknown; similar to unknown proteins from B. subtilis3.83.3
lspASignal peptidase II3.43.6
pyrRTranscriptional attenuation of the pyrimidine operon/uracil phosphoribosyltransferase activity3.52.1
ylqDUnknown; similar to unknown proteins3.73.2
frrRibosome recycling factor3.02.1
pksCInvolved in polyketide synthesis3.33.0
sspNSmall acid-soluble spore protein (minor)3.31.4
proJGlutamate 5-kinase16.217.7
proHPyrroline-5-carboxylate reductase22.524.7
yoaGUnknown; similar to unknown proteins3.82.6
yoaJUnknown; similar to extracellular endoglucanase precursor3.31.4
penPBeta-lactamase3.33.9
yocAUnknown; similar to transposon-related protein3.13.3
yocCUnknown; similar to unknown proteins7.07.3
yocHUnknown; similar to cell wall-binding protein12.313.8
dhaSAldehyde dehydrogenase3.03.8
yotHUnknown3.43.5
yomLUnknown3.01.6
bdbAThiol-disulfide oxidoreductase3.53.4
sunTSublancin 168 lantibiotic transporter4.14.6
bsaAPutative glutathione peroxidase4.34.2
sspLSmall acid-soluble spore protein (minor)3.92.0
ypsBUnknown; similar to unknown proteins3.73.2
ypqEUnknown; similar to phosphotransferase system enzyme II3.12.7
ypjDUnknown; similar to unknown proteins3.22.7
qcrCMenaquinol:cytochrome c oxidoreductase (cytochrome b/c subunit)3.45.9
yphFUnknown; similar to unknown proteins3.12.7
ypfDUnknown; similar to ribosomal protein S1 homolog3.22.5
ypdAUnknown; similar to thioredoxin reductase4.03.7
spoIIABAnti-sigma factor/serine kinase3.13.3
yqjXUnknown3.12.1
yqiIUnknown; similar to N-acetylmuramoyl-l-alanine amidase6.84.4
yqiHUnknown; similar to lipoprotein14.99.8
mntRTranscriptional regulator of manganese uptake4.23.2
gcvTProbable aminomethyltransferase3.12.2
yqxJUnknown12.813.0
yqxIUnknown8.710.9
yqaOUnknown; similar to phage-related protein4.33.0
yrdRUnknown; similar to unknown proteins3.72.5
yraGUnknown; similar to spore coat protein3.92.0
yrvCUnknown; similar to unknown proteins4.75.1
ysfCUnknown; similar to glycolate oxidase subunit3.71.8
citZCitrate synthase II (major)4.36.3
ytxGUnknown; similar to general stress protein3.23.4
yteVUnknown3.01.7
yukCUnknown; similar to unknown proteins6.05.3
yukDUnknown; similar to unknown proteins3.72.3
yuxIUnknown3.83.9
yukJUnknown3.52.8
lipAProbable lipoic acid synthetase4.43.8
yusFUnknown3.02.5
opuBCCholine ABC transporter (choline-binding protein)4.85.2
opuBACholine ABC transporter (ATP-binding protein)7.99.3
yvaWUnknown; similar to unknown proteins from B. subtilis9.09.4
yvzAUnknown6.15.4
yvcBUnknown4.03.8
yvcAUnknown12.710.1
degUTwo-component response regulator involved in degradative enzyme and competence regulation3.93.6
ywqJUnknown; similar to unknown proteins from B. subtilis4.03.2
ywqIUnknown; similar to unknown proteins from B. subtilis4.34.0
ywqHUnknown4.44.1
ywfHUnknown; similar to 3-oxoacyl-acyl-carrier protein reductase3.02.7
ywdAUnknown4.24.2
yxiDUnknown; similar to unknown proteins3.02.6
yydJUnknown4.13.9
yydIUnknown; similar to ABC transporter (ATP-binding protein)6.25.3
yydHUnknown5.65.0
yydGUnknown6.27.2
rapGResponse regulator aspartate phosphatase3.02.6
phrGPhosphatase (RapG) regulator10.79.4
  • a Sorted according to the order in the B. subtilis genome. Members of the DegS/DegU regulon are boldfaced.

  • b Derived from the SubtiList database.

  • c Ratio between the signal strength in cells propagated under the conditions indicated and the signal strength in cells continuously growing in synthetic medium with 5 μM FeCl3 and no extra NaCl added.