TABLE 3.

Susceptibilities of E. coli strains to toxic compounds

StrainMIC (μg/ml)a of:
OXAEMNOVDXRACRCVEBRMBR6GTPPBENZSDSDOC
W3104>256128>512>128256128512>51225651264>512>40,000
W3104Δhns>25664>512>128256128512>51225651264>512>40,000
W3104ΔacrAB14328161168484645,000
W3104ΔacrABΔemrKY14328161168484645,000
W3104ΔacrABΔmdtEF14328161168484645,000
W3104ΔacrABΔacrEF14328161168484645,000
W3104ΔacrABΔacrEFΔemrKY14328161168484645,000
W3104ΔacrABΔacrEFΔmdtEF14324161168484645,000
W3104ΔacrABΔacrEFΔmdtEFΔemrKY14324161168484645,000
W3104ΔacrABΔtolC0.5222818848416156
W3104ΔacrABΔhns6432128>1286412851251225625632>512>40,000
W3104ΔacrABΔhnsΔtolC0.5222818848432156
W3104ΔacrABΔhnsΔemrKY6432128>1286412851251225625632>512>40,000
W3104ΔacrABΔhnsΔmdtEF6416128>128646451251225625616>512>40,000
W3104ΔacrABΔhnsΔacrEF41632>12832864321288812810,000
W3104ΔacrABΔhnsΔacrEFΔemrKY41632>12832864321288812810,000
W3104ΔacrABΔhnsΔacrEFΔmdtEF12162161168484642,500
W3104ΔacrABΔhnsΔacrEFΔmdtEFΔemrKY12162161168484642,500
W3104ΔacrABΔhnsΔevgAS3232128>1286412851251225625632>512>40,000
W3104ΔacrABΔhnsΔacrEFΔevgAS21632>12832864161288812810,000
W3104ΔacrABΔydeO14328161168484645,000
W3104ΔacrABΔhnsΔydeO6432128>1286412851251225625632>512>40,000
  • a MIC determinations were repeated at least three times. Boldfaced values differ from the MIC of W3104ΔacrAB by a factor of more than 4. Abbreviations: OXA, oxacillin; EM, erythromycin; NOV, novobiocin; DXR, doxorubicin; ACR, acriflavine; CV, crystal violet; EBR, ethidium bromide; MB, methylene blue; R6G, rhodamine 6G; TPP, tetraphenylphosphonium bromide; BENZ, benzalkonium chloride; SDS, sodium dodecyl sulfate; DOC, sodium deoxycholate.