TABLE 1.

MIC and MBC for bacteria in whole biofilm effluent, planktonic cultures, and detached large clumps

CellsMIC (μg/ml)MBC (μg/ml)b
UnsonicatedSonicatedUnsonicatedSonicated
Whole biofilm effluent1.0 ± 2.11.1 ± 1.647.8 ± 2.653.0 ± 2.1
Planktonic culture0.9 ± 1.91.0 ± 1.913.5 ± 1.2*13.5 ± 2.0*
Detached large clumpsa0.4 ± 0.00.3 ± 0.1>20,0000.8 ± 1.5**
  • a Values for detached large clumps cannot numerically be compared to whole effluent and planktonic cultures due to differences in test methodology (see Materials and Methods).

  • b *, P = 0.001 comparing MBC for whole biofilm effluent and planktonic culture; **, P < 0.001 comparing MBC for sonicated and unsonicated detached large clumps.