TABLE 2.

Characteristics of putative tgs genes in the genome of M. tuberculosis

tgs geneIdentitya (%)Active-site motifTheoretical molecular mass (kDa)Theoretical pI
Rv3130c100.0HHCMADG50.710.11
Rv337142.8HHCMAGAMSAAHLLARLCDDADG48.99.48
Rv3740c29.5HHALVDG48.49.35
Rv022128.8HHALADG51.97.90
Rv3480c28.0HHSLIDG53.36.10
Rv3734c27.7HHALIDG49.36.36
Rv142526.9HHAIVDG50.15.79
Rv089526.9HHALADG53.910.38
Rv308726.7HHAYSDG52.66.93
Rv176026.3HHAVVDG54.16.27
Rv308825.9HHALIDG50.99.58
Rv228525.1HHCAVDG47.77.70
Rv2484c22.5SHAVTDG52.37.78
Rv3234c22.0HQALING30.49.83
Rv3233c14.5No motif20.94.69
  • a Since the Rv3130c-encoded enzyme showed the highest TGS activity, amino acid sequence identities of the other tgs gene products were compared to it by pairwise alignment with ALIGN, available at http://xylian.igh.cnrs.fr/bin/align-guess.cgi.