TABLE 3.

Data collection and crystallographic analysis

ParameterData for indicated complex
N109AN109A-CipN109A-R6GN109A-NafN109A-EtN109A-MC
Space groupR32R32R32R32R32R32
Cell constants (Å)a = b = 144.4, c = 518.9, α = β = 90, γ = 120a = b = 144.1, c = 518.8, α = β = 90, γ = 120a = b = 144.4, c = 518.4, α = β = 90, γ = 120a = b = 144.5, c = 519.4, α = β = 90, γ = 120a = b = 145.0, c = 519.4, α = β = 90, γ = 120a = b = 144.9, c = 516.7, α = β = 90, γ = 120
Resolution (Å)3.27 (3.44-3.27)3.23 (3.55-3.23)3.82 (4.00-3.82)3.27 (3.44-3.27)3.20 (3.40-3.20)3.56 (3.78-3.56)
Completeness (%)99.6 (98.9)100 (99.2)100 (98.6)96.8 (94.5)100 (99.1)100 (99.4)
Rsym (%)8.6 (48.2)7.2 (29.3)10.4 (48.2)10.3 (38.1)9.7 (37.6)10.1 (47.8)
Rwork/Rfree (%)26.7/33.326.6/33.628.0/33.526.7/34.927.2/34.125.6/33.3
Total no. of reflections874,453448,795374,4681,288,255894,586464,493
No. of unique reflections42,15537,82725,85939,54342,27734,163
I/σ(I)2.23.02.81.62.42.1