TABLE 4.

Repressed genes in suspension cultures due to the mqsR mutation (LB medium)a

Geneb no.FunctionExpression ratio
yieIb3716Hypothetical protein−27.9
crlb0240Transcriptional regulator of cryptic csgA gene for curli surface fibers−26.0
flhDb1892Regulator of flagellar biosynthesis, acting on class 2 operons−24.3
flub2000CP4-44 prophage; phase-variable outer membrane-associated fluffing protein−17.1
yncCb1450Hypothetical transcriptional regulator−16.0
cynXb0341Cyanate transport−14.9
ansPb1453l-Asparagine permease−11.3
phnDb4105Periplasmic binding protein component of Pn transporter−11.3
yeeRb2001CP4-44 prophage; putative membrane protein−9.8
yeeL_2b1979AMP nucleosidase−8.6
creDb4400Tolerance to colicin E2−8.6
yjgLb4253Hypothetical protein−8.0
flhCb1891Regulator of flagellar biosynthesis acting on class 2 operons−7.5
yieJb3717Hypothetical protein−7.5
ydeVb1511Putative kinase−7.0
aisb2252Protein induced by aluminum−7.0
yraIb3143Putative chaperone−7.0
ytfKb4217Hypothetical protein−7.0
ycgWb1160Hypothetical protein−6.5
yciEb1257Hypothetical protein−6.5
yidSb3690Hypothetical protein−6.5
ybbYb0513Possible uracil transporter−5.7
yciFb1258Hypothetical protein−5.7
yahOb0329Hypothetical protein−5.3
yjcHb4068Hypothetical protein−5.3
ydcVb1443Putative ABC transporter permease protein−4.6
yncGb1454Hypothetical GSTb-like protein−4.6
spfb3864Nontranslated RNA−4.6
yjcOb4078Hypothetical protein−4.6
ymgBb1166Hypothetical protein−4.3
ymgCb1167Hypothetical protein−4.3
yeaQb1795Hypothetical protein−4.3
amyAb1927Cytoplasmic alpha-amylase−4.3
gatCb2092PTSc family enzyme IIC, galactitol specific−4.3
dsdXb2365Transport protein−4.3
ygdIb2809Hypothetical protein−4.3
b3254b3254Hypothetical protein−4.3
yiaGb3555Hypothetical protein−4.3
tra5_3b0372Putative transposase 5 of IS3−4.0
yhjSb3536Hypothetical protein−4.0
rbsCb3750d-Ribose high-affinity transport system−4.0
  • a Genes consistently repressed (P < 0.05) more than fourfold are shown, and those in boldface type were reported regulated by AI-2 (15, 36, 44).

  • b GST, glutathione S-transferase.

  • c PTS, phosphotransferase.