Gene name | Synonym | PE_PGRS gene expression under culture condition^{b} | ||||
---|---|---|---|---|---|---|

Log phase (6-10 days) | Hypoxia (30 days) | Nutrient depletion (30 days) | Low pH, 4.5 (30 days) | Intracellular growth in BMMO (6 days) | ||

PE_PGRS01 | Rv0109 | E (1.82) | E (0.83) | E (1.24) | E (1.34) | LE (0.46) |

PE_PGRS14 | Rv0834c | HE (2.19) | E (1.10) | HE (2.56) | E (1.26) | E (1.30) |

PE_PGRS16 | Rv0977 | E (1.10) | E (0.76) | HE (2.35) | E (1.14) | HE (2.72) |

PE_PGRS18 | Rv0980c | LE (0.26) | LE (0.15) | E (0.84) | E (1.23) | LE (0.26) |

PE_PGRS24 | Rv1325c | E (1.60) | E (0.75) | E (1.09) | E (1.76) | E (0.68) |

PE_PGRS26 | Rv1441c | E (1.77) | LE (0.46) | LE (0.29) | E (0.58) | LE (0.38) |

PE_PGRS27 | Rv1450c | NE (0) | NE (0) | NE (0) | NE (0) | NE (0) |

PE_PGRS30 | Rv1651c | E (0.99) | E (0.91) | E (0.73) | E (1.33) | E (0.74) |

PE_PGRS33 | Rv1818c | E (1.82) | E (0.73) | E (0.88) | E (1.04) | E (0.90) |

PE_PGRS34 | Rv1840c | HE (2.04) | E (1.17) | HE (2.11) | E (1.84) | E (1.23) |

PE_PGRS35 | Rv1983 | HE (2.67) | E (1.25) | E (1.74) | E (1.92) | E (1.25) |

PE_PGRS44 | Rv2591 | E (0.71) | NE (0) | NE (0) | NE (0) | NE (0) |

PE_PGRS45 | Rv2615c | E (0.98) | E (0.78) | E (1.30) | E (0.98) | E (1.12) |

PE_PGRS50 | Rv3345c | NE (0) | NE (0) | NE (0) | NE (0) | NE (0) |

PE_PGRS51 | Rv3367 | E (0.52) | NE (0) | NE (0) | NE (0) | NE (0) |

PE_PGRS55 | Rv3511 | E (1.51) | NE (0) | LE (0.14) | E (0.5) | LE (0.16) |

↵

*a*Shown are differential expression patterns of PE_PGRS genes of*M. tuberculosis*Erdman relative to expression of the 16S rRNA gene, as studied by duplex RT-PCR. Selected PE_PGRS genes of*M. tuberculosis*Erdman were studied under various physiological conditions. The expressed gel bands were semiquantitated as net intensity (pixel) by using Kodak 1D image analysis software.↵

*b*The PE_PGRS gene expression levels relative to the 16S rRNA gene expression level are shown in parentheses and are defined as follows: HE, high expression (>2.0); E, expression (0.5 to 2.0); LE, low expression (<0.5); NE, not expressed (0).