TABLE 2.

Mutation rates and products for 10 E. coli O157:H7 strains

Strain or data group and locusRepeat motif (bp)nbTotal no. of mutationsMutation rateTotal no. of insertionsNo. of single-repeat insertionsNo. of multiple-repeat insertionsTotal no. of deletionsNo. of single-repeat deletionsNo. of multiple-repeat deletions
ATCC 700927
    O157-369122.0E-05220000
    O157-4339211.0E-05000110
    O157-557/308633.2E-05220110
    O157-969022.1E-05110101
    O157-10694323.2E-04302010211
    O157-1169419.9E-06110000
    O157-1769532.9E-05220110
    O157-1968611.1E-05000110
    O157-36a79322.0E-05110110
    O157-37a68011.2E-05110000
    O157-4559519.8E-06000110
    Total495.0E-04403010972
    %81.661.220.418.414.34.1
01A7146
    O157-689613.9E-05110000
    O157-969562.3E-04211431
    O157-10695187.0E-041082862
    O157-2569214.0E-05110000
    O157-36a78914.2E-05110000
    Total271.2E-03151231293
    %55.644.411.144.433.311.1
01A6820
    O157-269513.9E-05110000
    O157-369527.8E-05000220
    O157-4339513.9E-05110000
    O157-10695103.9E-04431642
    O157-1769014.1E-05000110
    O157-36a79413.9E-05110000
    Total166.5E-04761972
    %43.837.56.356.343.812.5
H6436
    O157-369631.2E-04211110
    O157-1069641.5E-04330110
    O157-1399214.0E-05110000
    Total83.2E-04651220
    %75.062.512.525.025.00.0
F6750
    O157-10693156.0E-04743853
    O157-2569014.1E-05110000
    O157-36a79014.1E-05110000
    Total176.9E-04963853
    %52.935.317.647.129.417.6
DEC4C
    O157-369314.0E-05000110
    O157-969214.0E-05110000
    O157-1069183.3E-04642202
    O157-1169613.9E-05110000
    O157-2569513.9E-05110000
    Total125.1E-04972312
    %75.058.316.725.08.316.7
Spain 401
    O157-557/308714.3E-05101000
    O157-969413.9E-05110000
    O157-10694103.9E-04413651
    O157-1398314.5E-05110000
    O157-1769214.0E-05110000
    O157-36a79114.1E-05000110
    O157-37a69241.6E-04321110
    Total198.6E-041165871
    %57.931.626.342.136.85.3
Spain 41
    O157-1158614.3E-05000110
    O157-10696176.6E-041091761
    O157-1968614.3E-05110000
    O157-36a79513.9E-05000101
    Total208.2E-0411101972
    %55.050.05.045.035.010.0
EC536 (wtc)
    O157-6810013.7E-05110000
    O157-9610013.7E-05000110
    O157-106100103.7E-04550523
    O157-11610051.9E-04101422
    O157-17610013.7E-05110000
    Total186.7E-048711055
    %44.438.95.655.627.827.8
EC1212 (mutS)
    O157-3610013.7E-05110000
    O157-6810013.7E-05000101
    O157-9610013.7E-05110000
    O157-106100124.5E-04752541
    O157-11610027.4E-05000220
    Total176.3E-04972862
    %52.941.211.847.135.311.8
Combined data for
        all wt PSPE
        populations
    O157-11513.4E-06000110
    O157-2613.5E-06110000
    O157-3683.2E-05431440
    O157-43326.6E-06110110
    O157-557/3041.4E-05321110
    O157-6826.6E-06220000
    O157-96113.6E-05541642
    O157-1061244.0E-04795722453015
    O157-11672.3E-05321422
    O157-13926.7E-06220000
    O157-17662.0E-05440220
    O157-19627.0E-06110110
    O157-25631.0E-05330000
    O157-36a772.3E-05440321
    O157-37a651.8E-05431110
    O157-45513.4E-06000110
    Total1866.4E-041168927705020
    %62.447.814.537.626.910.8
  • a Locus is on pO157 plasmid.

  • b Number of lineages with usable data.

  • c wt, wild type.