TABLE 3.

Mouse colonization densities with H. pylori strain X47 and antisense constructs in CJB/6J micea

StrainNo. of mice infected/total no. of miceNo. of CFU/g stomach ± SD
Mock (1× PBS)0/50
WT X475/5(1.01 ± 0.13) × 107
X47rdxA::aphA35/5(1.03 ± 0.30) × 107
X47rdxA::AS1563-25/5(1.00 ± 0.05) × 107
  • a Five mice each were infected with strain X47, X47rdxA::aphA3, or X47rdxA::AS1563-2, and 3 weeks postinfection, bacterial load was determined (CFU/g stomach) as described in the text.