TABLE 1.

Cholate derivatives induce colony formation by C. difficile spores

Cholate derivative added to BHISaCFU recovery (%)b
MeanSD
TA100
GA86.317.2
CA75.110.3
CDCA<0.0001c
UA<0.0001c
  • a Spores were serially diluted and spread on BHIS agar containing 0.1% taurocholate (TA), glycocholate (GA), cholate (CA), chenodeoxycholate (CDCA), or ursodeoxycholate (UA).

  • b Data are percentages relative to the value obtained with BHIS(TA) and are means of three independent experiments.

  • c CFU for CDCA and UA were below the limit of detection for this experiment.