TABLE 1.

Composition of SCFM

ComponentsConcn (mM)a
Ions
    Na+66.6
    K+15.8
    NH4+2.3
    Ca2+1.7
    Mg2+0.6
    Cl79.1
    NO30.35
    PO42−2.5
    SO42−0.27
Amino acids
    Serine1.4
    Threonine1.0
    Alanine1.8
    Glycine1.2
    Proline1.7
    Isoleucine1.1
    Leucine1.6
    Valine1.1
    Aspartate0.8
    Glutamate1.5
    Phenylalanine0.5
    Tyrosine0.8
    Tryptophan0.01
    Lysine2.1
    Histidine0.5
    Arginine0.3
    Ornithine0.7
    Cysteine0.2
    Methionine0.6
Other
    Glucose3.2
    Lactate9
    FeSO4 (μM)b3.6
  • a SCFM component concentrations are based on the average concentrations measured in CF sputum samples (see Tables S1 to S3 in the supplemental material for raw data). Amino acid values do not include those present within peptides but instead represent “free” levels in CF sputum. Values in this table have been rounded for clarity.

  • b The iron level is adapted from previous studies (6, 46, 57, 58).