TABLE 1.

Selected genetic and phenotypic properties of A. baumannii genomes

GenomeAccession no.Genome size (bp)No. of genesSource (reference)Size of RI (kb)Beta-lactamase gene(s)Plasmid-carried beta-lactamase geneResistance gene(s)Resistance gene(s)MICb
Class AClass CClass DTetra-cyclineChloram-phenicolTrimetho-prim-sulfagyrA/parC QRDRaAME geneAmpi-cillinAmpicillin-sulbactamPiperacillin-tazobactamCef-azolinCeftri-axoneCef-epimeMero-penemImi-penemTige-cyclineAztreo-namGenta-micinAmi-kacinTobra-mycinTrimethoprim-sulfamethoxazoleCipro-floxacin
AB0057ABJM010000014,050,5133,853WRAMC42 + 18blaTEM-1Two copies of ampCblaOXA-69, blaOXA-23tetAcatTwo copies of sulI, dhfrXRRaphA1, aacC1, aadA1≥32≥32≥128≥64≥64≥64≥16≥164≥64≥16≤2≤1160≥4
AB307-0294CP0011723,760,9813,458Buffalo, NYampCblaOXA-69dhfrXRS≥32≤2≤4≥64168≤0.25≤1≤0.5≥322≤2≤1≤202
AYECU4591413,936,2913,607France (51)86blaVEB-1ampCblaOXA-69, blaOXA-10tetAcat, cmlAFour copies of sulI, dhfrX, dhfrIRRaphA1, aadB, two copies of aadA1, aacC1R851211≥512RRRRR
AB900ABXK000000003,913,289WRAMCampCblaOXA-51-likedhfrXSS16≤2≤4≥64162≤0.25≤1≤0.5≥32≤1≤2≤1≤20≤0.25
ATCC 17978CP0005213,976,7473,791ATCC (43)ampCblaOXA-51sulI, dhfrXSS16≤2≤4≥64162≤0.25≤1≤0.5≥64≤1≤2≤1160≤0.25
ACICUCP0008633,904,1163,667Rome, Italy (20)17ampCblaOXA-66, blaOXA-20Two copies of blaOXA-58sulI, dhfrXRSaac3RRRRRRRRRR
SDFCU4682303,421,9542,913Louse in France (51)blaOXA-75dhfrXSSNDND
ADP1CR5438613,598,6213,325Soil (3)ampCdhfrX
  • a RR, resistance-associated Ser83Leu mutation found in gyrA and Ser80Ile mutation found in parC; SS, susceptibility-associated alleles in both gyrA and parC; RS, resistance-associated mutation found only in gyrA.

  • b R, resistant. Numbers in bold indicate resistance, and numbers in italics indicate intermediate susceptibility. Resistance data were published previously for AYE (15, 36), SDF (14, 24), and ACICU (20).