TABLE 2.

Criteria for directionality of LSPs

CharacteristicInserted regionDeleted region
Distribution in:
    M. avium subsp. paratuberculosisPresentAbsent
    Other M. avium strainsAbsentPresent
    M. intracellulareAbsentPresent
    G+C contentLow (<65%)Normal (65 to 71%)
Gene content:
    Mycobacterial orthologuesNo/fewYes
    Phagelike ORFs (e.g., integrase)YesNo
Flanking regions:
    Gene(s)Single, split geneOne or more truncated genes
    tRNAsPresentAbsent