TABLE 3.

Genes differentially expressed in an elevated c-di-GMP background

PA no.GeneChange (fold)Function
PA0020−1.6Hypothetical protein
PA0026plcB−1.9Phospholipase C
PA0408pilG−1.6Response regulator, twitching motility
PA0409pilH−1.9Response regulator, twitching motility
PA0652vfr−1.5Regulator of virulence
PA1077flgB−2.1Flagellar basal body rod protein
PA1078flgC−2.3Flagellar basal body rod protein
PA1079flgD−1.8Flagellar basal body rod modification
PA1080flgE−1.9Flagellar hook protein
PA1081flgF−2.4Flagellar basal body rod protein
PA1082flgG−2.0Flagellar basal body rod protein
PA1083flgH−2.0Flagellar L-ring protein precursor
PA1086flgK−1.7Flagellar hook-associated protein
PA1087flgL−1.9Flagellar hook-associated protein type 3
PA1089−2.0Hypothetical protein
PA1093−2.1Hypothetical protein
PA1094fliD−2.0Flagellar capping protein
PA1095−1.8Hypothetical protein
PA1096−2.0Hypothetical protein
PA1098fleS−1.8Two-component sensor, flagellum regulation
PA1099fleR−2.2Two-component regulator, flagellum regulation
PA1100fliE−1.7Flagellar hook-basal body complex
PA1101fliF−1.8Flagellum M-ring outer membrane protein
PA1441−2.0Hypothetical protein
PA1452flhA−1.8Flagellar biosynthesis protein
PA1456cheY−1.6Chemotaxis response regulator
PA1545−2.2Hypothetical protein
PA1705pcrG−2.0Regulator in type III secretion
PA1718pscE−1.8Type III export protein PscE
PA2654−2.4Methyl-accepting chemotaxis transducer
PA2761−3.1Hypothetical protein
PA3351flgM−1.5Anti-sigma factor, flagellum regulation
PA3526motY−1.9Sodium-driven flagellum motor protein
PA3713spdH−2.6Spermidine dehydrogenase
PA3762−2.4Hypothetical protein
PA4221fptA−2.9Fe(III)-pyochelin outer membrane receptor
PA4296pprB−1.9Two-component response regulator
PA4307pctC−7.2Methyl-accepting chemotaxis transducer
PA4309pctA−2.1Methyl-accepting chemotaxis transducer
PA4310pctB−1.7Methyl-accepting chemotaxis transducer
PA4523−5.1Hypothetical protein
PA4616−3.3Probable C4-dicarboxylate-binding protein
PA4633−2.3Methyl-accepting chemotaxis transducer
PA4704−2.2Hypothetical protein
PA5040pilQ−1.8Type 4 fimbrial biogenesis protein
PA5041pilP−1.9Type 4 fimbrial biogenesis protein
PA5042pilO−2.3Type 4 fimbrial biogenesis protein
PA5043pilN−2.0Type 4 fimbrial biogenesis protein
PA5044pilM−2.0Type 4 fimbrial biogenesis protein
PA5072−2.2Methyl-accepting chemotaxis transducer
PA5122−1.8Hypothetical protein
PA5139−1.7Hypothetical protein
PA5404−2.3Hypothetical protein
PA01695.1Putative diguanylate cyclase (GGDEF protein)
PA01704.4Hypothetical protein
PA01713.9Hypothetical protein
PA01723.6Hypothetical protein
PA2231pslA2.4Polysaccharide biosynthesis protein
PA2232pslB4.7Polysaccharide biosynthesis protein
PA24064.3Hypothetical protein
PA24074.6Probable adhesion protein
PA24405.4Putative polysaccharide deacteylase
PA24415.7
PA25602.0Hypothetical protein
PA33402.2Hypothetical protein
PA38191.7Hypothetical protein
PA3901fecA1.7Fe(III) dicitrate transport protein
PA43122.1Hypothetical protein
PA46249.7Hypothetical protein
PA462511.7Putative hemagglutinin-adhesin
PA52121.6Hypothetical protein
PA55261.8Hypothetical protein