TABLE 1

Core and EHEC-specific sRNAs that contribute to EHEC pathogenesis

General process targetedsRNATarget RNAType of regulationDirect interactionReference(s)
AdherencesRNA103fimZPositivePredicted64
Global regulationAgvBgcvBNegativeYes63
Iron homeostasisAsxRfnsRNegativeYes63
Esr41BfrNegativeYes87
chuANegativeYes87
cirANegativeYes87
LEE and effectorsGlmY/ZLEE4NegativeYes130
LEE5NegativeUnknown130
nleAPositivePredicted no64
espFuPositivePredicted direct130
sRNA56espAPositivePredicted no64
sRNA103espAPositivePredicted no64
sRNA350UnknownPositiveUnknown64
ArllerNegativeAntisense sRNA119
Esr055UnknownPositiveUnknown147
Spot42sepLNegativeYes87, 111
RyhBgrlRANegativeYes112
MgrRgrlRNegativeYes112
MetabolismsRNA56ureGPositivePredicted direct64
MotilityEsr41fliCPositiveUnknown175