TABLE 2

Intracellular concentrations of pGpG and c-di-GMP in B. subtilis WT and ΔnrnA ΔnrnB strains

SubstanceDaughter ionConcn (mean ± SD) (μM)aFold change (mutant/WT)b
WT 168ΔnrnA ΔnrnB mutant
pGpG1ND1.8 ± 0.6NA
2ND1.8 ± 0.4NA
c-di-GMP10.8 ± 0.22.4 ± 0.53.0
20.9 ± 0.13.0 ± 0.93.3
  • a ND, not detected.

  • b NA, not applicable.