Table 2

KinB regulon genes with increased expression due to rpoN deletion

Gene group and PA locusGeneProductFold changea
Pyochelin genes
    PA4220fptBHypothetical protein25.1
    PA4221fptAFe(III)-pyochelin outer membrane receptor precursor7.1
    PA4222pchIProbable ATP-binding component of ABC transporter14.3
    PA4223pchHProbable ATP-binding component of ABC transporter11.7
    PA4224pchGPyochelin biosynthetic protein PchG21.3
    PA4225pchFPyochelin synthetase13.2
    PA4226pchEDihydroaeruginoic acid synthetase16.8
    PA4227pchRTranscriptional regulator PchR2.2
    PA4228pchDPyochelin biosynthesis protein PchD7.7
    PA4229pchCPyochelin biosynthetic protein PchC5.3
    PA4230pchBSalicylate biosynthesis protein PchB25.5
    PA4231pchASalicylate biosynthesis isochorismate synthase12.2
Pilus genes
    PA4651cupE4Pilin assembly chaperone CupE419.8
    PA4293pprAProbable pili assembly chaperone12.5
    PA4294Hypothetical protein12.1
    PA4296pprBTwo-component response regulator, PprB3.5
    PA4297tadGTadG2.7
    PA4298Hypothetical protein5.0
    PA4299tadDTadD13.1
    PA4300tadCTadC7.4
    PA4301tadBTadB5.9
    PA4302tadATadA ATPase5.0
    PA4303tadZTadZ7.1
    PA4304rcpARcpA11.7
    PA4305rcpCRcpC13.4
    PA4306flpType IVb pilin, Flp26.1
Antibiotic efflux genes
    PA1874Hypothetical protein14.8
    PA1875opmLProbable outer membrane protein precursor19.5
    PA1876Probable ATP-binding/permease fusion ABC transporter8.3
    PA1877hlyDProbable secretion protein5.0
    PA4293pprATwo-component sensor kinase PprA12.5
    PA4294pprBResponse regulator PprB12.1
    PA4205mexGHypothetical protein8.5
    PA4206mexHProbable efflux membrane fusion protein precursor7.4
    PA4207mexIProbable efflux transporter4.9
    PA4208opmDProbable outer membrane protein precursor5.1
    PA4218ampPAmpP β-lactamase permease6.1
    PA4219ampOAmpO12.0
Quorum-sensing genes
    PA3622rpoSSigma factor RpoSNS
    PA1430lasRTranscriptional regulator LasRNS
    PA1432lasIAutoinducer synthesis protein LasINS
    PA1871lasALasA protease precursor12.0
    PA3724lasBElastase LasB3.2
    PA3476rhlIAutoinducer synthesis protein RhlI3.3
    PA3477rhlRTranscriptional regulator RhlRNS
    PA3478rhlBRhamnosyltransferase chain B10.0
    PA3479rhlARhamnosyltransferase chain A10.7
    PA1245Hypothetical protein2.8
    PA1246aprDAlkaline protease secretion protein AprD3.5
    PA1247aprEAlkaline protease secretion protein AprE3.6
    PA1248aprFAlkaline protease secretion outer membrane protein AprF2.6
    PA1249aprAAlkaline metalloproteinase precursorNS
Nitrogen regulation genes
    PA0518nirMCytochrome c551 precursor2.3
    PA0519nirSNitrite reductase precursor2.8
    PA0520nirQRegulatory protein NirQ4.0
    PA0523norCNitric-oxide reductase subunit C5.1
    PA0524norBNitric-oxide reductase subunit B2.6
    PA0525norDProbable dinitrification protein NorD6.1
    PA3391nosRRegulatory protein NosR2.6
Other genes and virulence factors
    PA2300chiCChitinase16.2
    PA2570lecALecA PA-I galactophilic lectin16.1
    PA2788Probable chemotaxis transducer14.7
    PA4351Probable acyltransferase14.0
    PA3126lbpAHeat shock protein IbpA7.1
  • a NS, nonsignificant.