TABLE 2

Comparison of the MMAR_1663-MMAR_1668 genomic regions in M. marinum and M. tuberculosis

M. marinum geneM. tuberculosis gene% Amino acid identityProposed function (reference)a
MMAR_1663Rv3038c87Conserved hypothetical ortholog, MeT; essential for in vitro growth in M. tuberculosis (54)
MMAR_1664Rv3037c77Conserved hypothetical ortholog, SAM-MeT; essential for growth in macrophages in M. tuberculosis (63)
MMAR_1665Rv3036c (TB22.2)79Conserved hypothetical secreted/outer membrane protein; similar to MPT-64
MMAR_1666Not conservedNAbHypothetical membrane protein
MMAR_1667Rv303582Conserved protein; ortholog, pyrrolo-quinoline quinone/8-blade beta propeller
Essential for in vitro growth in M. tuberculosis (54)
MMAR_1668Rv3034c93Possible maltose O-transferase family; essential for in vitro growth in M. tuberculosis (54)
  • a Proposed functions collected from MycoBrowser, the TB Database, and NCBI BLAST. MeT, methyltransferase.

  • b NA, not applicable.