TABLE 3

Drug susceptibilities of LVS, PM2006 (Δlnt), and complemented strains

DrugaDose (μg/disc)Zone of inhibition (mm)b
LVSPM2006PM2006/pMP822PM2006/pMP874LVS/pMP882
Globomycin15020 ± 124 ± 1#25 ± 016 ± 115 ± 0
Rifampin528 ± 236 ± 1##38 ± 227 ± 1ND
  • a Other compounds tested that did show any difference between LVS and PM2006 strain included the following (with dose in micrograms per disc in parentheses): tetracycline (30), vancomycin (30), sodium dodecyl sulfate (750), polymyxin B (300 IU), ethidium bromide (5), amoxicillin-clavulanic acid (30/10).

  • b The average diameter of the zone of inhibition (including filter disc) in millimeters, ± the standard deviation. ND, not determined. Statistical significance compared to result with LVS: #, P < 0.008; ##, P < 0.003. pMP822, vector control; pMP874, lnt+; pMP882, lsp+.