TABLE 4

Survival and replication of the Δlnt mutant in THP-1 cells

StrainTHP-1 cells (CFU/ml) aftera:
6 h24 h
LVS6.0 × 103 ± 04.7 × 105 ± 0.6 × 105
PM2006 Δlnt5.3 × 103 ± 1.1 × 103*4.0 × 105 ± 2.0 × 105**
  • a Each experiment was performed in triplicate, and the results are averages ± standard deviations. Compared to the wild type, LVS, results with the lnt mutant showed no significant differences: *, P < 0.332; **, P < 0.592.