TABLE 6

Drug susceptibilities of N. gonorrhoeae F62 and the Δlnt mutant PM2475

DrugaDose (disc−1)Zone of inhibition (mm)b
F62PM2475
Globomycin150 μg24 ± 029 ± 0
Rifampin5 μg30 ± 134 ± 1#
Polymyxin B300 IU9 ± 012 ± 0##
Vancomycin30 μg14 ± 117 ± 1##
  • a Compounds showing no difference between F62 and PM2475 included the following (with the dose, in micrograms per disc, in parentheses): tetracycline (30), sodium dodecyl sulfate (750), ethidium bromide (5), amoxicillin-clavulanic acid (30/10).

  • b Average diameter of the zone of inhibition (including the filter disc) ± the standard deviation. Significance of difference from result with F62: #, P < 0.008; ##, P < 0.020.