σ factors
Research Article | SpotlightLysozyme Resistance in Clostridioides difficile Is Dependent on Two Peptidoglycan DeacetylasesClostridioides difficile is the leading cause of hospital-acquired diarrhea. C. difficile is highly resistant to lysozyme. We previously showed that the csfV operon is required for lysozyme resistance. Here, we used CRISPR-Cas9 mediated mutagenesis and CRISPRi knockdown to show that...