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essential genes

  • Free
    A First Look at the Essential Genes of <span class="named-content genus-species" id="named-content-1">Pseudomonas protegens</span>
    Commentary
    A First Look at the Essential Genes of Pseudomonas protegens

    Transposon insertion sequencing is a useful tool to identify the genes that are essential for a bacterial species to grow and divide effectively. In this issue of Journal of Bacteriology, Fabian et al. present the first set of transposon insertion sequencing data highlighting the genes essential to the plant-commensal species Pseudomonas protegens strain Pf-5...

    Bradley E. Poulsen
  • Free
    cyAbrB Transcriptional Regulators as Safety Devices To Inhibit Heterocyst Differentiation in <em>Anabaena</em> sp. Strain PCC 7120
    Research Article
    cyAbrB Transcriptional Regulators as Safety Devices To Inhibit Heterocyst Differentiation in Anabaena sp. Strain PCC 7120

    Spore formation in Bacillus subtilis and Streptomyces has been extensively studied as models of prokaryotic nonterminal cell differentiation. In these organisms, many cells/hyphae differentiate simultaneously, which is governed by a network in which one regulator stands at the top. Differentiation of heterocysts in Anabaena sp. strain PCC 7120 is...

    Akiyoshi Higo, Eri Nishiyama, Kota Nakamura, Yukako Hihara, Shigeki Ehira
  • Open Access
    Global Analysis of Genes Essential for <span class="named-content genus-species" id="named-content-1">Francisella tularensis</span> Schu S4 Growth <em>In Vitro</em> and for Fitness during Competitive Infection of Fischer 344 Rats
    Research Article
    Global Analysis of Genes Essential for Francisella tularensis Schu S4 Growth In Vitro and for Fitness during Competitive Infection of Fischer 344 Rats

    The intracellular bacterial pathogen Francisella tularensis causes a disease in humans characterized by the rapid onset of nonspecific symptoms such as swollen lymph glands, fever, and headaches. F. tularensis is one of the most infectious bacteria known and following pulmonary exposure can have a...

    Philip M. Ireland, Helen L. Bullifent, Nicola J. Senior, Stephanie J. Southern, Zheng Rong Yang, Rachel E. Ireland, Michelle Nelson, Helen S. Atkins, Richard W. Titball, Andrew E. Scott
  • Open Access
    Research Article
    Genome-Wide Identification by Transposon Insertion Sequencing of Escherichia coli K1 Genes Essential for In Vitro Growth, Gastrointestinal Colonizing Capacity, and Survival in Serum
    Alex J. McCarthy, Richard A. Stabler, Peter W. Taylor
  • Research Article
    The Essential Genome of Burkholderia cenocepacia H111
    Steven Higgins, Maria Sanchez-Contreras, Stefano Gualdi, Marta Pinto-Carbó, Aurélien Carlier, Leo Eberl
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