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exotoxins

  • Open Access
    Timing Is Everything: Impact of Naturally Occurring <em>Staphylococcus aureus</em> AgrC Cytoplasmic Domain Adaptive Mutations on Autoinduction
    Research Article
    Timing Is Everything: Impact of Naturally Occurring Staphylococcus aureus AgrC Cytoplasmic Domain Adaptive Mutations on Autoinduction

    Virulence factor expression in Staphylococcus aureus is regulated via autoinducing peptide (AIP)-dependent activation of the sensor kinase AgrC, which forms an integral part of the agr quorum sensing system. In response to bound AIP, the cytoplasmic domain of AgrC (AgrC-cyt) undergoes conformational changes resulting in dimerization, autophosphorylation, and...

    Tim J. Sloan, Ewan Murray, Maho Yokoyama, Ruth C. Massey, Weng C. Chan, Boyan B. Bonev, Paul Williams
  • Research Article
    Identification of the Regulon of AphB and Its Essential Roles in LuxR and Exotoxin Asp Expression in the Pathogen Vibrio alginolyticus
    Xiating Gao, Yang Liu, Huan Liu, Zhen Yang, Qin Liu, Yuanxing Zhang, Qiyao Wang
  • MOLECULAR BIOLOGY OF PATHOGENS
    vfr, a Novel Locus Affecting Cysteine Protease Production in Streptococcus pyogenes
    Yongsheng Ma, Amy E. Bryant, Dan B. Salmi, Eric McIndoo, Dennis L. Stevens
  • MOLECULAR BIOLOGY OF PATHOGENS
    Membrane Morphology and Leukotoxin Secretion Are Associated with a Novel Membrane Protein of Aggregatibacter actinomycetemcomitans
    Claude V. Gallant, Maja Sedic, Erin A. Chicoine, Teresa Ruiz, Keith P. Mintz
  • MOLECULAR BIOLOGY OF PATHOGENS
    The Carriage Population of Staphylococcus aureus from Mali Is Composed of a Combination of Pandemic Clones and the Divergent Panton-Valentine Leukocidin-Positive Genotype ST152
    Raymond Ruimy, Aminata Maiga, Laurence Armand-Lefevre, Ibrahim Maiga, Amadou Diallo, Abdel Karim Koumaré, Kalilou Ouattara, Sambou Soumaré, Kevin Gaillard, Jean-Christophe Lucet, Antoine Andremont, Edward J. Feil
  • MOLECULAR BIOLOGY OF PATHOGENS
    Regulation of Aggregatibacter (Actinobacillus) actinomycetemcomitans Leukotoxin Secretion by Iron
    Nataliya V. Balashova, Roger Diaz, Sergey V. Balashov, Juan A. Crosby, Scott C. Kachlany
  • GENE REGULATION
    Identification and Characterization of Bicistronic speB and prsA Gene Expression in the Group A Streptococcus
    Yongsheng  Ma, Amy E. Bryant, Dan B. Salmi, Susan M. Hayes-Schroer, Eric McIndoo, Michael J. Aldape, Dennis L. Stevens
  • MOLECULAR BIOLOGY OF PATHOGENS
    Regulation of SpeB in Streptococcus pyogenes by pH and NaCl: a Model for In Vivo Gene Expression
    Jennifer A. Loughman, Michael Caparon
  • Plant Microbiology
    The Global Arginine Regulator ArgR Controls Expression of argF in Pseudomonas syringae pv. phaseolicola but Is Not Required for the Synthesis of Phaseolotoxin or for the Regulated Expression of argK
    José Luis Hernández-Flores, Karina López-López, Rogelio Garcidueñas-Piña, Alba E. Jofre-Garfias, Ariel Alvarez-Morales
  • Genomics and Proteomics
    Mosaic Structure and Molecular Evolution of the Leukotoxin Operon (lktCABD) in Mannheimia (Pasteurella) haemolytica, Mannheimia glucosida, and Pasteurella trehalosi
    Robert L. Davies, Susan Campbell, Thomas S. Whittam

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