phosphodiesterase
Research ArticleCyclic di-GMP-Mediated Regulation of Gene Transfer and Motility in Rhodobacter capsulatusGene transfer agents (GTAs) are virus-like particles that move cellular DNA between cells. In the alphaproteobacterium Rhodobacter capsulatus, GTA production is affected by the activities of multiple cellular regulatory systems, to which we have now added signaling via the second messenger dinucleotide molecule bis-(3′-5′)-cyclic dimeric GMP (c-di-GMP). Similar to the...
MinireviewMaking and Breaking of an Essential Poison: the Cyclases and Phosphodiesterases That Produce and Degrade the Essential Second Messenger Cyclic di-AMP in BacteriaCyclic di-AMP is a second-messenger nucleotide that is produced by many bacteria and some archaea. Recent work has shown that c-di-AMP is unique among the signaling nucleotides, as this molecule is in many bacteria both essential on one hand and toxic upon accumulation on the other.
- Research ArticleOptogenetic Module for Dichromatic Control of c-di-GMP Signaling