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proteomics

  • <span class="named-content genus-species" id="named-content-1">Bacillus subtilis</span> Regulators MntR and Zur Participate in Redox Cycling, Antibiotic Sensitivity, and Cell Wall Plasticity
    Research Article
    Bacillus subtilis Regulators MntR and Zur Participate in Redox Cycling, Antibiotic Sensitivity, and Cell Wall Plasticity

    Manganese and zinc are essential transition metals involved in many fundamental cellular processes, including protection against external oxidative stress. In Bacillus subtilis, Zur and MntR are key transcriptional regulators of zinc and manganese homeostasis, respectively. In this work, proteome analysis of...

    Paola Randazzo, Jamila Anba-Mondoloni, Anne Aubert-Frambourg, Alain Guillot, Christine Pechoux, Jasmina Vidic, Sandrine Auger
  • A Universal Stress Protein That Controls Bacterial Stress Survival in <span class="named-content genus-species" id="named-content-1">Micrococcus luteus</span>
    Research Article | Spotlight
    A Universal Stress Protein That Controls Bacterial Stress Survival in Micrococcus luteus

    Bacteria tolerate severe external stresses, including antibiotics, through a nonreplicative persistent (NRP) survival state, yet the proteins regulating this survival state are largely unknown. We show a specific universal stress protein (UspA616) controls the NRP state in Micrococcus luteus. Usps are widely conserved across bacteria, but their biological function(s)...

    Spencer Havis, Abiodun Bodunrin, Jonathan Rangel, Rene Zimmerer, Jesse Murphy, Jacob D. Storey, Thinh D. Duong, Brandon Mistretta, Preethi Gunaratne, William R. Widger, Steven J. Bark
  • Tyrosine Phosphorylation as a Widespread Regulatory Mechanism in Prokaryotes
    Minireview
    Tyrosine Phosphorylation as a Widespread Regulatory Mechanism in Prokaryotes

    Phosphorylation events modify bacterial and archaeal proteomes, imparting cells with rapid and reversible responses to specific environmental stimuli or niches. Phosphorylated proteins are generally modified at one or more serine, threonine, or tyrosine residues. Within the last ten years, increasing numbers of global phosphoproteomic surveys of prokaryote species have revealed an abundance of tyrosine-phosphorylated proteins.

    ...
    Landon J. Getz, Cameron S. Runte, Jan K. Rainey, Nikhil A. Thomas
  • Importance of Pyruvate Sensing and Transport for the Resuscitation of Viable but Nonculturable <em>Escherichia coli</em> K-12
    Research Article
    Importance of Pyruvate Sensing and Transport for the Resuscitation of Viable but Nonculturable Escherichia coli K-12

    Viable but nonculturable (VBNC) bacteria do not form colonies in standard medium but otherwise retain their metabolic activity and can express toxic proteins. Many bacterial genera, including Escherichia, Vibrio, and Listeria, have been shown to enter the VBNC state upon exposure to adverse conditions, such as low temperature, radiation, and starvation. Ultimately, these organisms pose a public health risk...

    Cláudia Vilhena, Eugen Kaganovitch, Alexander Grünberger, Magdalena Motz, Ignasi Forné, Dietrich Kohlheyer, Kirsten Jung
  • Research Article
    Species-Specific Interactions of Arr with RplK Mediate Stringent Response in Bacteria
    Priyanka Agrawal, Rajagopal Varada, Shivjee Sah, Souvik Bhattacharyya, Umesh Varshney
  • Research Article
    A Proteomic Signature of Dormancy in the Actinobacterium Micrococcus luteus
    Sujina Mali, Morgan Mitchell, Spencer Havis, Abiodun Bodunrin, Jonathan Rangel, Gabriella Olson, William R. Widger, Steven J. Bark
  • Research Article
    Comprehensive Spatial Analysis of the Borrelia burgdorferi Lipoproteome Reveals a Compartmentalization Bias toward the Bacterial Surface
    Alexander S. Dowdell, Maxwell D. Murphy, Christina Azodi, Selene K. Swanson, Laurence Florens, Shiyong Chen, Wolfram R. Zückert
  • Genomics and Proteomics
    Expressed Genome of Methylobacillus flagellatus as Defined through Comprehensive Proteomics and New Insights into Methylotrophy
    Erik L. Hendrickson, David A. C. Beck, Tiansong Wang, Mary E. Lidstrom, Murray Hackett, Ludmila Chistoserdova
  • Genomics and Proteomics
    Identification of Chlamydia trachomatis Outer Membrane Complex Proteins by Differential Proteomics
    Xiaoyun Liu, Mary Afrane, David E. Clemmer, Guangming Zhong, David E. Nelson
  • Plant Microbiology
    Proteomic Alterations Explain Phenotypic Changes in Sinorhizobium meliloti Lacking the RNA Chaperone Hfq
    Lise Barra-Bily, Catherine Fontenelle, Gwenael Jan, Maud Flechard, Annie Trautwetter, Shree P. Pandey, Graham C. Walker, Carlos Blanco

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