swarming
Research Article | SpotlightIdentification of Three New GGDEF and EAL Domain-Containing Proteins Participating in the Scr Surface Colonization Regulatory Network in Vibrio parahaemolyticusA key survival decision, in the environment or the host, is whether to emigrate or aggregate. In bacteria, c-di-GMP signaling almost universally influences solutions to this dilemma.
CommentaryPQS Signaling for More than a Quorum: the Collective Stress Response Protects Healthy Pseudomonas aeruginosa PopulationsIn this issue, Bru et al. connect Pseudomonas aeruginosa PQS signaling secretion during stress response to swarming behavior (J.-L. Bru, B. Rawson, C. Trinh, K. Whiteson, et al., J Bacteriol 201:e00383-19, 2019, https://doi.org/10.1128/JB.00383-19).
Research ArticlePQS Produced by the Pseudomonas aeruginosa Stress Response Repels Swarms Away from Bacteriophage and AntibioticsWe uncover a phage- and antibiotic-induced stress response in the clinically important opportunistic pathogen Pseudomonas aeruginosa. Phage-infected P. aeruginosa subpopulations are isolated from uninfected subpopulations by the production of a stress-induced signal. Activation of the stress...
Research ArticleSingle Cells Exhibit Differing Behavioral Phases during Early Stages of Pseudomonas aeruginosa SwarmingNumerous bacteria exhibit coordinated swarming motion over surfaces. It is often challenging to assess the behavior of single cells within swarming communities due to the limitations of identifying, tracking, and analyzing the traits of swarming cells over time. Here, we show that the behavior of Pseudomonas aeruginosa swarming cells can vary substantially in the...
Special Issue Meeting ReviewFlagellar Stators Activate a Diguanylate Cyclase To Inhibit Flagellar StatorsThe bacterial secondary metabolite cyclic di-GMP is a widespread, cytoplasmic signal that promotes a physiological transition in which motility is inhibited and biofilm formation is activated. A paper published in this issue (A. E. Baker, S. S. Webster, A. Diepold, S. L. Kuchma, E.
Research ArticleCell Shape and Population Migration Are Distinct Steps of Proteus mirabilis Swarming That Are Decoupled on High-Percentage AgarHow surfaces influence cell size, cell-cell interactions, and population migration for robust swarmers like P. mirabilis is not fully understood. Here, we have elucidated how cells change length along a spectrum of sizes that positively correlates with increases in agar concentration, regardless of population migration. Single-cell phenotypes can be decoupled from...
Research ArticlePrevention of Surface-Associated Calcium Phosphate by the Pseudomonas syringae Two-Component System CvsSRBacteria are capable of precipitating and dissolving minerals. We previously reported the characterization of the two-component system CvsSR in the plant-pathogenic bacterium Pseudomonas syringae. CvsSR responds to the presence of calcium and is important for causing disease. Here, we show that CvsSR controls the ability of the bacterium to prevent calcium phosphate...
Research Article | SpotlightAssembly Order of Flagellar Rod Subunits in Bacillus subtilisBacteria rotate propeller-like flagella to find and colonize environmental niches. The flagellum is a complex machine, and the understanding of its structure is still incomplete. Here, we characterize and biochemically define the assembly order of the subunits that make up the axle-like rod. The rod is a critical structure for the assembly of subsequent components and is central to our understanding of how the flagellum is anchored but...
- Research ArticleSwarmer Cell Development of the Bacterium Proteus mirabilis Requires the Conserved Enterobacterial Common Antigen Biosynthesis Gene rffG
Proteus mirabilis swarm motility has been implicated in pathogenesis. We have found that cells deploy multiple uncharacterized strategies to handle cell envelope stress beyond the Rcs phosphorelay when attempting to engage in swarm motility. While RcsB is known to directly inhibit the master transcriptional regulator for swarming, we have shown an additional role for...