Thermus thermophilus
- Research ArticleGlutamate Dehydrogenase from Thermus thermophilus Is Activated by AMP and Leucine as a Complex with Catalytically Inactive Adenine Phosphoribosyltransferase Homolog
GDH, which catalyzes the synthesis and degradation of glutamate using NAD(P)(H), is a widely distributed enzyme among all domains of life. Mammalian GDH is regulated allosterically by multiple metabolites, in which the antenna helix plays a key role to transmit the allosteric signals. In contrast, bacterial GDH was believed not to be regulated allosterically because it lacks the antenna helix. We previously reported that GDH from...
- GENETICS AND MOLECULAR BIOLOGYAn Extreme Thermophile, Thermus thermophilus, Is a Polyploid Bacterium
- STRUCTURAL BIOLOGYStructural Characterization of the Ribosome Maturation Protein, RimM