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Tn-seq

  • Research Article
    A Genetic Determinant of Persister Cell Formation in Bacterial Pathogens

    Antibiotic treatment of P. aeruginosa residing in the lung of cystic fibrosis patients is ineffective. Treatment failure is attributed in part to antibiotic-tolerant phenotypic variants known as persister cells. Understanding how these cells emerge will likely inform future therapeutic strategies. In the current study, we identified carB, which codes for the...

    David R. Cameron, Yue Shan, Eliza A. Zalis, Vincent Isabella, Kim Lewis
  • Research Article
    The Essential Genome of Burkholderia cenocepacia H111
    Steven Higgins, Maria Sanchez-Contreras, Stefano Gualdi, Marta Pinto-Carbó, Aurélien Carlier, Leo Eberl
  • Open Access
    Research Article
    Genome Scale Mutational Analysis of Geobacter sulfurreducens Reveals Distinct Molecular Mechanisms for Respiration and Sensing of Poised Electrodes versus Fe(III) Oxides
    Chi Ho Chan, Caleb E. Levar, Fernanda Jiménez-Otero, Daniel R. Bond
  • Minireview
    Implementation and Data Analysis of Tn-seq, Whole-Genome Resequencing, and Single-Molecule Real-Time Sequencing for Bacterial Genetics
    Peter E. Burby, Taylor M. Nye, Jeremy W. Schroeder, Lyle A. Simmons
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