Tn-seq
- Research ArticleA Genetic Determinant of Persister Cell Formation in Bacterial Pathogens
Antibiotic treatment of P. aeruginosa residing in the lung of cystic fibrosis patients is ineffective. Treatment failure is attributed in part to antibiotic-tolerant phenotypic variants known as persister cells. Understanding how these cells emerge will likely inform future therapeutic strategies. In the current study, we identified carB, which codes for the...
- Research ArticleThe Essential Genome of Burkholderia cenocepacia H111